In what case did the Supreme Court first exercise the power of judicial review? Laws and Institutions In what case did the Supreme Court first exercise the power of judicial review? A. Marbury v. Madison B. McCulloch v. Maryland C. Brown v. Board of Education D. Dred Scott v. Sandford E. Martin v. Hunter's Lessee Answer: A. Marbury v. Madison Learn More : Share this Share on FacebookTweet on TwitterPlus on Google+